Breakthrough Prize in Fundamental Physics Awarded to Event Horizon Telescope Team

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Almost 30 MIT-partnered scientists will partake in the prize, while David Jay Julius ’77 successes Breakthrough Prize in Life Sciences; assistant professor of mphysics Max Metlitski shares New Horizons prize with Xie Chen PhD ’12 and Michael Levin PhD ’06.

The Event Horizon Telescope (EHT) Collaboration, including researchers and specialists from MIT, will get a 2020 Breakthrough Prize in Fundamental Physics. The group is being respected for making the principal direct location of a black hole. Assistant professor of physics Max Metlitski and a few MIT alumni  are likewise accepting honors from the Breakthrough Prize Foundation.

The $3 million fundamental physics prize will be shared similarly with the 347 EHT scientists from around the globe who co-created the six papers distributed on April 10, 2019, which revealed the identification of the supermassive black hole at the core of Messier 87, or M87, a system inside the Virgo galaxy cluster.

The new laureates will be perceived at an honors function in Mountain View, California, on Nov. 3.

Source: Event Horizon Telescope Awarded Breakthrough Prize in Fundamental Physics

Researchers Made New Cell Phone App to Monitor TB Treatment 

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For tuberculosis patients, agreeing to a full course of treatment can be overwhelming and troublesome. In any case, another test directed by MIT scientists in Kenya, in a joint effort with the digital health organization Keheala, demonstrates that an advanced program utilized on cell phones helps patients effectively complete their medicines.

The program made intelligent correspondence among patients and suppliers — instead of, state, single direction updates about medicine — and furthermore utilized social science bits of knowledge to help spur patients to proceed with their recuperation regimens.

After the test mediation, just 4 percent of tuberculosis patients had ineffective treatment results. For examination, 13 percent of patients in a control gathering, who did not utilize the stage, didn’t complete their treatment.

“Patients who we bolstered with our portable stage were 66% less inclined to neglect to finish treatment,” says Erez Yoeli, an exploration researcher at the MIT Sloan School of Management and co-creator of a recently distributed paper plotting the study’s outcomes.

Source: Digital Program on Mobile Phones Tames Tuberculosis

Scientists have Devised New Powerful Method to Augment T-cell Therapy

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A promising better approach to treat a few kinds of cancer is to program the patient’s very own T cells to kill the carcinogenic cells. This methodology, named CAR-T cell therapy, is presently used to battle a few kinds of leukemia, yet so far it has not functioned admirably against strong tumors, for example, lung or breast tumors.

MIT scientists have now formulated an approach to super-charge this treatment so it could be utilized as a weapon against cancer. The examination group built up an antibody that drastically supports the antitumor T cell populace and enables the cells to energetically attack strong tumors.

In an investigation of mice, the scientists found that they could totally take out strong tumors in 60 percent of the animals that were given T-cell treatment alongside the promoter inoculation. Built T cells all alone had no impact.

 

“By including the immunization, a CAR-T cell treatment which had no effect on survival can be intensified to give a total reaction in the greater part of the animals,” says Darrell Irvine, who is the Professor with arrangements in Biological Engineering and Materials Science and Engineering, a partner executive of MIT’s Koch Institute for Integrative Cancer Research, an member from the Ragon Institute of MGH, MIT, and Harvard, and the senior author of the investigation.

 

Reference:

Leyuan Ma, et al., “Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor,” Science 12 Jul 2019: Vol. 365, Issue 6449, pp. 162-168; DOI: 10.1126/science.aav8692