Yale Researcher Devise drinkable cocktail for Alzheimer Therapy

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drinkable Alzheimer cocktail

Yale researchers have fabricated a drinkable cocktail of designer mix that meddles with a pivotal initial step of Alzheimer’s and even reestablishes memories in mice, reported in Cell Reports.

 

The binding of amyloid beta peptides to prion proteins triggers a course of destruction measures in the advancement of Alzheimer’s — collection of plaques, a damaging immune system reaction, and harm to neural synapses.

 

"We needed to discover particles that may therapeutically affect this immune system response," said senior author Stephen Strittmatter, the Vincent Coates Professor of Neurology, professor of neuroscience, and director of the Yale Alzheimer Disease Research Center.

Reference:

Erik C. Gunther, et al., “Rescue of Transgenic Alzheimer’s Pathophysiology by Polymeric Cellular Prion Protein Antagonists,” Cell Reports, 2018; doi:10.1016/j.celrep.2018.12.021