Mouse pups with same-sex parents born in China advancing stem cells and gene editing technologies

bimaternal mouse

Mouse puppies with same-sex guardians conceived in China utilizing stem cells and gene editing


Analysts at the Chinese Academy of Sciences could deliver solid mice with two moms that proceeded to have ordinary posterity of their own. Mice from two fathers were likewise conceived yet made due for two or three days. The work, published October 11 in the Cell Stem Cell, takes a gander at what makes it so trying for creatures of a similar sex to deliver posterity and proposes that a portion of these hindrances can be defeated utilizing foundational stem cells and focused on gene editing.

bipaternal mice


Li, Z.-K., et al. “Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions.” Cell Stem Cell.

Z.-K. Li et al. Generation of uniparental mice from hypomethylated haploid ESCs with imprinting region deletions. Cell Stem Cell. Published online October 11, 2018. doi: 10.1016/j.stem.2018.09.004.

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